Product description

Size

100 µg

Product code

BP6BU100

Human Insulin-like growth factor binding protein-6 (IGFBP-6) is a 213 amino acid glycosylated protein which is a member of a family of six circulating proteins which bind IGF-I and IGF-II with high affinity and modulate their metabolic and mitogenic effects. IGFBP-6 is unique among IGFBPs for its IGF-II binding specificity since it binds IGF-II with a 20-70 fold higher affinity than IGF-I. IGFBP-6 inhibits growth of a number of IGF-II-dependent cancers, including rhabdomyosarcoma, neuroblastoma and colon cancer. Although the major action of IGFBP-6 appears to be inhibition of IGF-II actions, a number of studies suggest that it may also have IGF-independent actions.

Fact sheets

Human IGFBP-6 specifications

Human IGFBP-6SDS

Related products

• Human IGFBP-1
• Human IGFBP-2
• Human IGFBP-3
• Human IGFBP-4
• Human IGFBP-5

自1990年以来，GroPep Bioreagents便已向大学，研究机构，生物技术和制药公司的研究人员开发，制造和销售生长因子，抗体和相关蛋白试剂。

我们的任务是在准确和可靠的技术建议的支持下，为科学家提供高质量的试剂。

我们科学人员的强大研究背景和经验是我们为客户提供“动手”建议的关键。

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我们通过会议赞助和向会员提供折扣来支持IGF协会