Product description

Size

20 µg

Product code

BP1BU020

Human Insulin-like growth factor binding protein-1 (IGFBP-1) is a 234 amino acid protein which is a member of a family of six circulating proteins that bind IGF-I and IGF-II with high affinity and modulate their metabolic and mitogenic effects. The liver, ovarian granulosa cells, decidualized endometrium and a number of other cell types produce native human IGFBP-1. IGFBP-1 binds both IGF-I and IGF-II. Serum IGFBP-1 levels are regulated by insulin-induced inhibition of IGFBP-1 production. IGFBP-1 appears to inhibit smooth muscle migration in response to IGF-I or IGF-II and to stimulate wound healing in response to IGF-II. Native IGFBP-1 is predominantly a lower molecular weight species of 218 amino acids and 3-4 phosphorylated forms.

Fact sheets

Human IGFBP-1 specifications

Human IGFBP-1 SDS

Related products

• Human IGFBP-2
• Human IGFBP-5

自1990年以来，GroPep Bioreagents便已向大学，研究机构，生物技术和制药公司的研究人员开发，制造和销售生长因子，抗体和相关蛋白试剂。

我们的任务是在准确和可靠的技术建议的支持下，为科学家提供高质量的试剂。

我们科学人员的强大研究背景和经验是我们为客户提供“动手”建议的关键。

我们了解我们的产品并倾听您的需求。

我们通过会议赞助和向会员提供折扣来支持IGF协会